The phrase "affect a broad spectrum" is correct and usable in written English.
It can be used when discussing the impact or influence of something across a wide range of areas or subjects.
Example: "The new policy is expected to affect a broad spectrum of industries, from technology to agriculture."
Alternatives: "impact a wide range" or "influence a diverse array".
The detection and study of terrestrial exoplanets promises to usher in a new era in science and will affect a broad spectrum of diciplines.
Therefore, calphostin C and Ro-31-8220, twidelyely used and structurally distinct inhibitors which affect a broad spectrum of PKC family kinases, were tested for their ability to prevent Epo-stimulated activation of MEKs and Erks.
Some authors have found significant enrichment of age-dependent CpG hypermethylation at DNA-binding factors and at transcription factors (Hernandez et al., 2011), suggesting that deregulation of these so-called master genes could affect a broad spectrum of biological pathways and, consequently, could explain the wide phenotypic alterations of aging.
Furthermore, where relative-staff conflicts in general tend to be centred around moments of crisis (end-of-life decision making, patients' deaths) [ 6, 7], we found that in a multi-ethnic critical care context, conflicts tend to be present during multiple care phases, affect a broad spectrum of care aspects and may assault the core of actors' identities.
M6A modification affects a broad spectrum of cellular functions, including maintenance of the pluripotency of embryonic stem cells (ESCs) and the reprogramming of somatic cells into induced pluripotent stem cells (iPSCs).
The developmental action of Notch is highly pleiotropic, affecting a broad spectrum of tissues, cellular fates, and developmental events.
The diversity of protein classes found to be regulated by FLT3 inhibitor suggests that FLT3 affects a broad spectrum of signaling pathways and cell functions not limited to proliferation and survival.
Heat stress affects a broad spectrum of cellular components and metabolism, often causing irreversible damage to plant growth and development.
Annotation and analysis based on gene ontology terms suggested that waterlogging affected a broad spectrum of functional categories.
