Infections, coagulopathy, and neoplasms represent the three major aetiologic groups.
Human herpesvirus type 8 (HHV-8) is the aetiologic agent of Kaposi's sarcoma (KS).
Human Rhinovirus (HRV) is the most important aetiologic agent of common cold in adults and children.
Human Bocavirus (HBoV) has recently been identified and implicated as an aetiologic agent of lower respiratory tract infection in children.
Laveran first described pigmented bodies in humans to define a protozoan as the aetiologic agent of malaria.
Although Japanese encephalitis virus was initially suspected, the predominant aetiologic agent was subsequently confirmed to be Nipah virus, a novel paramyxovirus related to but distinct from Hendra virus.
Parvovirus B19, the only known pathogenic human parvovirus is the aetiologic agent of erythema infectiosum, transient aplastic crisis, pure red cell aplasia, and hydrops fetalis.
Concomitantly, the high degree of interindividual variation in the current population facilitates fine mapping efforts to pinpoint the aetiologic polymorphisms.
As an oral bacterial pathogen, Streptococcus mutans has been known as the aetiologic agent of human dental caries.
Mycobacterium tuberculosis, the aetiologic agent of tuberculosis, is unusual in possessing only one type II topoisomerase, DNA gyrase [6].
Porphyromonas gingigivalis is a gram-negative oral anaerobe which has been implicated as one of the major aetiologic agents of periodontitis in adults [1].
