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In the Adolescent Supplement of the National Comorbidity Survey, childhood adversities were found to predict disruptive behavior disorders most strongly and anxiety disorders least strongly [ 3].
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However, it is still not clear which specific domains of adult cognition are associated with early socioeconomic conditions and to what extent current socioeconomic conditions, especially education, can mitigate or overcome the effects of early socioeconomic adversity that were found in this and earlier studies.
In Model 1, significant effects of G × E interaction, adversity, gender, and SES were found [fitness index of this model: χ = 61.216 (P <0.001), -2log likelihood = 37.706, discrimination accuracy = 96.9%].
No significant associations were found between any of the childhood adversities and lifetime plans in the group of ideators.
Significant associations were found between hsCRP and childhood social adversity in the Canadian but not in the Latin American samples.
In girls but not boys, proximal life events were found to at least partially moderate the direct effect of childhood adversity on late adolescent depressive symptoms.
Additionally, in most cases these resources were found to have predominately promotive effects, generally being beneficial for children experiencing both low- and high- levels of adversity.
We examined the effect of various measures and types of adversities because, although different kinds of childhood adversities tend to co-occur [ 3, 7, 20], some adversities have been found to be stronger associated with later mental health outcomes than others (e.g., [ 3, 7, 8, 12]).
This 4-class model using 9 variables derived from 16 adversity indicators was found to be the most parsimonious solution.
For instance, growing up in a dysfunctional family, parental rearing styles, and early childhood adversities have all been found to be related to the development of BPD traits [ 9].
No significant G × E interaction between 5-HTTLPR genotype and adversity or main effects of genotype, adversity, and gender was found from these analyses (Table 5).
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