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Leonard Woolf led an exemplary life, rich in spite of its adversities (in addition to Virginia, two of his siblings and a sister-in-law committed suicide, and another sister was mentally unstable).
We studied the effect of the number of possibly stressful childhood adversities on telomere length by categorizing the sum score to four groups: 0 adversities, 1 adversity, 2 or 3 adversities, and 4 or more adversities, in addition to studying them one at a time.
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In addition to childhood adversities, smoking and duration of sleep affected telomere length.
However, current work on epigenetic programming of mice does suggest that differential changes in methylation in response to early-life adversity and aging apply to other genes in addition to AVP (Y. Wu, unpublished data).
Early life emotional adversity may make a contribution to adult cardiovascular disease in addition to the long-term biological effects of early life economic adversity.
I would like to suggest a perhaps more mundane factor in addition to triumphs of children over adversity in imagined worlds.
In addition to alcohol use disorders, childhood adversity is associated with an increased risk of PTSD (Widom 1999).
In addition to the main effect of the childhood adversity measure we included its interaction with a time-dependent variable indicating the period after childhood, that is, from age 12 onwards.
In addition to estimating the effect of each of the childhood adversity measures separately, we also fitted a model that included all three measures simultaneously.
Furthermore, in addition to potentially influencing the structural development of the brain, early life adversities may also be reflected in an imbalance in the function of noradrenergic and dopaminergic systems that have shown to play a role in ADHD [ 27].
In addition to socioeconomic and psychosocial, we further grouped the exposures into work related and non-work related adversities.
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