The phrase "adverse issues" is correct and usable in written English.
It can be used to describe problems or challenges that have negative effects or consequences in a particular context.
Example: "The company faced several adverse issues that impacted its overall performance in the market."
Alternatives: "negative factors" or "unfavorable circumstances".
In response to an inquiry on adverse issues with the program, on February 8 , 2007 Moosally submitted a statement to the United States House Committee on Armed Services Subcommittee on Seapower and Expeditionary Forces regarding Lockheed's construction of its portion of the LCS contract.
However, adverse issues related to the integration of a provirus such as insertional mutagenesis, promoter interference and positional effects have been highlighted by induction of malignancy in mouse models[ 8] and by the development of leukaemia in five patients in two clinical gene therapy trials[ 9, 10].
A designer could not ignore these factors in the smart building because the adverse effect of these issues on system performance is considerable.
This decision will be based on the findings of the interim analyses, the periodic monitoring, the occurrence of a serious adverse event, or other issues that possibly could affect continuation of the study.
Subjects are also strongly encouraged to discuss with the research staff anything they feel to be an adverse event or other issues that are problematic for them about the study.
Although SDF has been in use for a few decades without serious adverse effect, the safety issue of applying high concentration fluoride is still equivocal, especially in young children.
This article summarizes the issue of adverse event reporting in HSCT.
Similarly, the naivety of the patients to opioids may be an issue in adverse event incidence, and we were unable to analyse this data set by previous opioid exposure.
However, wet dust is subject to adverse caking issues which lead to a drastic reduction in the dispersibility of the particles.
Patient education could be strengthened for all patients with TB regarding adverse effect and compliance-related issues.
Because of these methodological issues, comparisons of adverse event rates within each group for Year 1 and subsequent years are not appropriate.
