Exact(4)
Hence understanding the role of early metabolic mediators of inflammatory responses to infection in particular oxysterols, will aid in the development of urgently needed host directed therapeutic and diagnostic design innovation to combat adverse infection outcomes and antibiotic resistance.
While antiviral drugs have the potential to reduce or prevent occurrence of serious adverse infection outcomes for treated individuals, our results show that at this low level of diagnosis antivirals have essentially no population-level effect in reducing overall transmission.
We have not modelled the potential which antiviral drugs have to reduce or prevent occurrence of serious adverse infection outcomes, which may well make antiviral treatment a worthwhile strategy even in scenarios where only a small stockpile is available or where only small numbers of (serious) cases are diagnosed.
28 Post-stroke pneumonia is a common adverse infection that affects up to one-third of acute stroke patients.
Similar(56)
Adaptive immune suppression may occur early in the course of pediatric septic shock and is associated with adverse infection-related outcomes.
As cell numbers were controlled for in our experimental model, this suggests that decreased cellular responsiveness in addition to lymphopenia may be associated with adverse infection-related outcomes in this cohort.
No serious adverse events (infection, paralysis or neurologic deficit) were reported.
There were no cases of anaphylaxis, major adverse reactions, infection, or local necrosis at the injection site.
Secondary outcome measures will include pain, active range of motion, elbow extension strength, and any adverse events (infection, secondary interventions) at 3 and 12 months.
Safety outcomes included adverse events, infections and infusion reactions.
Clinical data at each visit (e.g. weight, height, adverse events, infections etc).
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