The phrase "adverse differentiation" is correct and usable in written English.
It can be used in contexts discussing negative or unfavorable distinctions between entities, products, or situations.
Example: "The company's strategy led to adverse differentiation in the market, causing confusion among consumers."
Alternatives: "negative distinction" or "unfavorable differentiation".
We chose this concentration from earlier studies that demonstrated adverse effects on differentiation of PC12 cells without outright cytotoxicity (Jameson et al. 2007; Qiao et al. 2001; Slotkin et al. 2007b, 2008d).
As activated Creb was found primarily in the distal lung epithelium, and that the onset of the Creb1−/− defect occurred at the developmental stage where AECs first begin to differentiate (E16.5 E17.5), we reasoned that an absence of Creb1 would have an adverse effect on AEC differentiation.
Adipocytes in bone marrow exhibit severe adverse effect on osteoblast differentiation, proliferation, and function.
LVsh5/C46 treatment was nontoxic as assessed by cell growth and viability, was noninflammatory, and had no adverse effect on HSPC differentiation.
Oriented to reduce the adverse effects of numerical differentiation, integral equation formulations based on Green's function methods have been considered, in the chemical engineering fields.
Furthermore, REG4 expression was closely linked with mucinous tumors, differentiation and adverse prognosis of ovarian cancer.
However, in general, RASSF1A methylation in tumour tissue and corresponding body fluids often correlates with advanced tumour stage and grade, metastasis, poor tumour differentiation and adverse survival.
Autophagy is an evolutionarily conserved lysosomal degradation pathway that plays essential roles in maintaining cellular homeostasis and promoting cell survival, growth, and differentiation against adverse conditions [ 106; 106].
Our findings indicate that aberrant REG4 expression plays an essential role in early ovarian carcinogenesis and is closely linked to mucinous ovarian tumors, differentiation and adverse prognosis of ovarian cancer by modulating proliferation, apoptosis, migration and invasion.
In addition, exposure of fat-head minnow embryos to VZ at concentrations ranging from 90 to 1,200 μg/L did not result in any adverse effects on sexual differentiation or reproductive health (Makynen et al. 2000).
