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For example, exposure to thyroid-disrupting chemicals such as perchlorate during the fetal and early child development can produce adverse effects on neurologic development by decreasing TH levels; the same mild perturbations in TH levels would not present an adverse challenge to a healthy adult.
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The body has a large regenerative capacity to cope with the continuous adverse challenges of high-calorie diets, aging, inflammation, and wear and tear, as well as acute injuries such as myocardial infarction.
As a corollary, a disease pathway is viewed as the sum of alterations in one or several pathways whose combined effects result in the inability of the system to adjust to adverse challenges and is then manifested in the diseased state.
Various studies (Kassie et al. 2014; Oluoko-Odingo 2009; Pérez et al. 2015) have revealed the existence of an association between the level of education and adaptation against adverse environmental challenges.
Likewise, the adverse effect is challenge the availability of productivity in Ethiopia.
Challenge adverse legal rulings.
Alternatively, Oct4 overexpression may have adverse effects that challenge attempts to rescue the Oct4 knockdown phenotype.
In each treatment group, one volunteer developed transient grade 3 adverse effects after challenge, with nausea, vomiting, strong abdominal pain and diarrhoea.
The primary issue, according to Daston, is determining what type of signature constitutes an adverse effect; the challenge is to distinguish adverse responses to a chemical exposure from homeostatic responses that is, normal changes that may indicate a cell is disposing of a toxicant in a way that will not lead to lasting damage or that may not be related to the exposure at all.
Any adverse finding is challenged.
Jeffrey Levi, then the executive director of the National Gay and Lesbian Task Force, testified against Justice Kennedy at his confirmation hearings, saying that "his past opinions offer little hope to gays and lesbians challenging adverse treatment in the courts".
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CEO of Professional Science Editing for Scientists @ prosciediting.com