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Finally, we did not observe any significant qualitative adverse bone remodeling as we compared sequential radiographs for each patient.
Advanced polymer composite materials have closer stiffness to bone than metals, ceramics or polymers, and have been hypothesised to promote less adverse bone adaptation.
Two major causes of bone loss in the supporting bone are adverse bone remodeling in response to debris shed from the implant and stress-shielding.
We hypothesize that the new design will reduce the peri-prosthetic bone failure risk and adverse bone remodeling by restoring the natural load transfer in the femur.
Childhood and adolescence are crucial growth periods, thus, prevention of growth retardation and adverse bone health with the use of VPA may be addressed by judicious use of AEDs coupled with improved nutrition and promotion of weight-bearing activities.
Because of these various influences, the effect of exposure to a number of different organochlorines is likely to be difficult to predict; nonetheless, these animal studies suggest a possible causal relationship between organochlorine exposure and adverse bone effects.
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Concerns about specific adverse events (bone loss, oedema and congestive heart failure) with use of thiazolidinedione agents remain 24, however, and decisions to use these agents require careful balancing of risks and benefits.
AIs have adverse effects on bone turnover with a reduction of bone mineral density and an increase in the rate of fragility fractures.
Systemic nicotine may have a significant adverse impact on bone wound healing and inhibit the bone matrix-related gene expressions required for wound healing [ 14, 15].
Berley et al.[ 47] and Yamano et al.[ 48] indicated that systemic nicotine may have a significant adverse impact on bone wound healing and inhibit the bone matrix-related gene expressions required for wound healing.
We found little evidence that exposure to TCDD had an adverse relationship with bone health > 30 years later; in fact, some trends suggested better bone density.
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