If you can trace the advent of the problem to a specific event, it may help narrow down the likely suspects.
It should be noted that the study on the problem with knuckle cracking has been criticized for not accounting potential alternative explanations for the advent of these problems.
But thousands have recently fled, and the town is now crawling with soldiers, aid workers and United Nations personnel, the movable cast that marks the advent of a serious problem.
Producing high-quality crystals has always been a bottleneck to structure determination and, with the advent of proteomics, this problem is becoming increasingly acute.
Although labor and cost have decreased with the advent of novel technologies, the problem of variant interpretation has increased proportional to the range and sensitivity of the screening methods.
With the advent of digital computers, discrete problems can be solved readily even if the number of elements is very large.
However, the advent of HAART brought the new problem of immune recovery inflammatory syndrome.
As the advent of the digital age, the problem of expansion of knowledge and information will be solved for human being.
However, the advent of HAART brought the new problem of immune recovery inflammatory syndrome (IRIS), characterized by paradoxical worsening of treated opportunistic infection or unmasking of subclinical, untreated infection [1, 2].
Now, it would be overstating matters to say that this problem appears only from a contemporary perspective; there was some recognition of it in the ancient and medieval periods.[3] Still, before the advent of the experimental science, the problem was not strongly felt because experience was understood in a different way.
The advent of complex industrial water/wastewater management problems points to a need for effective systematic design for a sustainable solution.
