Sentence examples for advantageous mutations from inspiring English sources

This was achieved through the combination of an effective selection method for the amino acid positions to be mutated and the accumulation of advantageous mutations.

As the mutational effects get larger, the proportion of advantageous mutations out of all possible ones decreases, and so does the probability of improvement.

T. Ohta, "Evolution by gene duplication and compensatory advantageous mutations," Genetics 120 (1988): 841-847.

Alternatively, the aged SC population may favor the clonal dominance of SCs that carry advantageous mutations, as seen for the hematopoietic and intestinal stem cells34.

The "status quo" meant that gene function was already close to its optimum in general, and advantageous mutations were extremely rare.

Toward the end of the 1980s, however, increasing amounts of data showed the existence of slightly advantageous mutations and the effects of positive selection on them.

If both deleterious and advantageous mutations participate in tumor initiation, then we find an intermediate optimum for the compartment size.

We investigate the dependence of the dynamics of fixation of advantageous mutations on the topology of fitness landscapes.

Therefore, Ohta modified her original nearly neutral theory by incorporating the fate of slightly advantageous mutations, and proposed this modified theory as "nearly neutral theory of molecular evolution" in a series of two papers published in 1990 and1991.

Of course, if the fixation of slightly deleterious mutations is followed by that of slightly advantageous mutations, the function of the gene can be maintained in long-term evolution.

Advantageous mutations are ones that increase the efficiency of energy transfers within an ecosystem.