Dose-finding studies by Durham et al. and Didier et al. have identified that the most advantageous maintenance dose for SLIT with grass pollen is between 15 and 25 μg of major allergen daily.
Evidence accumulates that persistent inhibition of the VEGF pathway might be advantageous over intermittent dosing, although both dosing schedules have not been directly compared yet.
The absence of co-emitted high energetic gamma rays as they are emitted by 44Sc at high intensity (Eγ = 1157 keV [100%]), would be clearly advantageous regarding the dose burden to patients and medical staff.
Another possible explanation may be that the frequent intake of fish and PUFA may be advantageous in lower doses but disadvantageous in higher doses.
Thus, targeting SIRT3 to induce OSCC cell cytotoxicity in patients who have high SIRT3-expressing tumors may be advantageous, because lower doses of treatment would be required.
43 Some studies have shown that combinations of antioxidants can be beneficial for pathologies associated with increased oxidative stress, 44 and that such a strategy might be advantageous over higher doses of single antioxidants for treating mitochondriopathies, 45, 46 reproducing what is already present in nature, that is, a combination of antioxidant systems rather than a single system.
Here it is hypothesized that minimization of the integral dose is advantageous in radiotherapy planning.
From a clinical standpoint, high-pitch and high-temporal resolution scanning modes offer the possibility to provide examinations free of motion artefacts, potentially acquired without apnea, at a low radiation dose, all advantageous for respiratory patients.
Similarly, although a null effect was not excluded, advantageous effects of low dose steroids had a high probability of dependence upon patient underlying risk.
The short half-lives are advantageous since higher injected doses can be administered for improved image quality while still permitting an overall reduction in effective radiation dose.
