The phrase "advantage of expression" is not commonly used in written English and may sound awkward.
It could be used in contexts discussing the benefits of expressing thoughts or feelings, but it may require additional clarification for better understanding.
Example: "The advantage of expression in art allows individuals to convey their emotions and experiences in a unique way."
Alternatives: "benefit of expression" or "merit of expression".
Taking advantage of expression data from mouse Pax6Sey/Sey embryonic telencephalon [17], we next compared the 559 lens gene list (see above, Supporting information) with differentially expressed genes in E12 and E15 dorsal (cortex, Ctx), and E12 and E15 ventral (the ganglionic eminence, GE) telencephalon [17] as described in Methods.
One advantage of expression profiling methods for characterizing microglia is that they permit studies of genes not readily amenable to antibody staining (e.g., soluble chemokines/cytokines).
The advantage of expression analysis by Western blot, compared to dot-blots, is that this allows one to quantitate the expression levels of full-length constructs and eliminate the contribution from cleaved protein tag.
Another key advantage of expression profiling studies is that they also inform about the consequences of epigenomic modifications, as transcriptomes reflect not merely the output of DNA sequences, but also their interplay with non-genetic modifiers of gene expression.
We took advantage of expression profiling of ovarian and endometrial cancer cell lines treated with demethylating agents to identify candidates for epigenetically silenced tumor suppressor genes in epithelial ovarian cancer.
It should be kept in mind that spermatogenesis is much more efficient in mouse compared to man, yielding a much higher number of mature spermatozoa per gram testis weight per time unit, and a small selective advantage of expression of an X-linked gene in mouse spermatids may translate into an essential function in man.
Taking advantage of expression-profiling surveys performed in extended human populations [ 171- 174], systems biologists have started integrating physiopathology, network biology and DNA variations [ 175- 177], providing novel insights into the mechanisms of various diseases, such as diabetes [ 178] and obesity [ 179].
Given the advantages of expression data (e.g. tissue and condition specificity, and dynamics) developing computational methods for cross species analysis of this data remains an important challenge.
This highlights a further advantage of autologous expression over the often unsuccessful expression of human genes in E.coli [31].
To screen for mutations that enhance the expression of transgenes in C. elegans, we took advantage of the expression system of peIs304, in which a moderate increase in expression induction potential is converted to a drastic change from AIZ-OFF to AIZ-ON through the thresholding effect observed in AIZ.
We describe here a successful screen for mutations that generally enhance the expression of transgenes in somatic cells of C. elegans by taking advantage of this expression system.
