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A wide range of bias-correction methods are proposed in the scientific community, out of which the simple methods have the advantage of altering the RCMs' results as little as possible (Graham et al. 2007).
Environments alternating between low and high expression demands resulted in overall rather than differential changes in expression, which is explained by the concave shape of the cross-environmental tradeoff curve that limits the selective advantage of altering the regulatory response.
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In this study, we took advantage of genetically altered mice lacking GluR2 (GluR2−/−) or having a reduced level of GluR2 (GluR2+/−) to present evidence that a distinct synaptic signaling underlies this CP-AMPAR-dependent LTP.
We took advantage of genetically altered mice with no or reduced GluR2, thus allowing the expression of synaptic CP-AMPARs, to investigate the molecular signaling process during CP-AMPAR-induced synaptic plasticity at CA1 synapses in the hippocampus.
A fortuitous observation has allowed us to demonstrate that virulent phages have evolved the capacity to take advantage of this altered host cell state to increase their own production.
It may be speculated that members of the microbiome gain a selective advantage by altering cellular signaling via production of endocrine molecules in the form of secondary BAs.
To reduce the possibility that lagging chromosomes were the result of altered spindle morphology, we took advantage of a temperature-sensitive mutant (dhc-1 ct76)). dhc-1 ct76
The RFLP-SNP system [8], [9], which is an accurate and inexpensive mapping methodology that does not require specialized equipment, takes advantage of polymorphisms that alter restriction enzyme recognition sites.
A bolt of altered perspective.
Some of the most polymorphic regions of Stx2 are involved in receptor recognition [48] [50], suggesting that these changes confer a selective advantage, likely by altering host range specificity.
In this instance, pathway mapping suggests that only a subset of the genes in a pathway may confer a selective advantage when altered in a specific tissue type.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com