Exact(13)
Note that (d′ − r′) is the selective advantage coefficient.
The second example is the selective advantage coefficient.
Finding the values of initial mutation rate and the selective advantage coefficient also have potential applications in other related issues.
Thus our equation depends on four parameters, namely the initial mutation rate µ0, selective advantage coefficient s, transforming factor a, and the number of driver genes.
Our model has successfully predicted the values of several important parameters in cancer progression, such as the selective advantage coefficient, initial mutation rate and cell doubling time.
The averaged values of doubling time and selective advantage coefficient determined by our model are consistent with the predictions made by the published models.
Similar(46)
By using the same raw data, our proposed model predicted that different patient should have different selective advantage coefficients and different initial mutation rates.
Log transformation has the added advantage that coefficients can be readily interpreted as elasticities[ 3, 66].
Natural logs have the added advantage that coefficients can be readily interpreted as elasticities, offering a straightforward measure of the impact of capacity utilization on costs, the main focus of this analysis [ 71, 72].
The advantage of this coefficient is that it can be used to analyze the agreement of multiple raters, even if there are unequal sample sizes or missing data.
The advantage of kappa coefficient is its correction for the amount of agreement that can be expected to occur by chance.
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