In prospective population-based studies, weight loss has been found to be associated with dementia even at mild severity, increasing with advancing disease severity and duration [27].
With advancing complication severity, the sensitivity of the administrative database increased while the specificity decreased (Table 2).
In one study of 679 patients with AD in the United States, 61% had ≥3 medical comorbidities, and the number increased with advancing dementia severity.
With advancing clinical severity, bvFTD atrophy spreads throughout this Salience Network and into neighboring supervisory executive-control (Fig. 2) (Brambati et al. 2007b; Seeley et al. 2008) and possibly temporopolar emotional semantic systems in some patients (Whitwell et al. 2009a).
Individuals were categorized into minimal severity (≤4.0) representing no mobility aid use, intermediate severity (4.5 6.5) representing unilateral or bilateral mobility aid use, and advanced (≥7.0) severity representing primarily wheelchair use for mobility.
Longer ICU length of stay, advanced age, severity of hypoxemia according to Berlin classification, and higher SOFA score were risk factors for ICU mortality.
Type 2 diabetes is a progressive disease in which advancing condition or severity is generally presumed to have an increasing burden on overall health.
The manually segmented volumes appeared to decline more with advancing Alzheimer's disease severity, than did the auto-segmented volumes.
7 Our study paints a picture of a severe diarrhea illness with rapid onset that appeared to increase in severity with advancing age.
3 However, the majority of these survivors experience long-term sequelae of therapy which increase in prevalence and severity with advancing age 4 and result in shortened life expectancy.
