We propose that comprehensive, cell type-specific mappings of DNA and histone modifications, chromatin-associated RNAs, and chromosomal "loopings" and other determinants of three-dimensional genome organization will critically advance insight into the pathophysiology of the disease.
Diverse content and type of carbon nanofiller, microstructure of the conductive network in the matrix, and electromechanical responses of the nanocomposites under broadband-frequency strain are discussed, in conjunction with dynamic mechanical analysis and a theoretical nanoscale model, to advance insight into the sensing mechanism of the sensors.
Model-driven manipulation of our compounds promises to advance insight into how antitubulin drugs act upon tubulin.
Future analysis and modification of our compounds will advance insight into the colchicine site-drug interaction and promise to result in new anticancer compounds with optimal performance and, possibly, minimal toxicity.
Ethnic minority women are hindered by relatives from accessing care choices and costs, despite having advanced insight about government reforms to alleviate poverty.
These examples demonstrate how advancements in computation and simulation models yield new methods and techniques, which can advance insights on a variety of issues relating to crime and justice practices.
ABC surrounded the ice with hockey mavens (though not the Maven, Stan Fischler) like Brian Engblom and Darren Pang, who offered game-advancing insights and vignettes and did not display the sycophancy of Ahmad Rashad, NBC's designated player pal.
It is argued that insistence on the application of the objectivist principles to real information systems may hamper rather than advance insights and progress because of this.
These will advance insights and yield benefits to enhance collaborative research, utilise limited resources effectively and share data, technology and expertise.
Today's generation of identity management learns patterns and delivers advanced insights by ingesting vast amounts of identity, access and event data.
Advancing insights into fundamental mechanisms will be necessary in the development of novel anticancer strategies based on inhibition of angiogenesis.
