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The exciting methodological advances in sequence assembly and genome mapping have enabled even large and repeat-rich genomes to be unlocked48,50 and hold the promise of constructing reference-quality genome sequences, not only for a single cultivar, but also for representatives of major germplasm groups.
Advances in sequence genomics have resulted in an accumulation of a large number of protein sequences derived from genome sequences.
Moreover, formidable advances in sequence similarity searches make it possible to identify with a high fidelity proteins whose exact sequence is missing in the database, using their likeness to orthologues from other species.
Advances in sequence technology have lead to renewed efforts in the discovery and characterization of somatic mutations in different cancers.
In conclusion, we have benefited from two major advances in sequence analysis programs, namely the incorporation of predicted secondary structure in homology detection software (HHpred [ 85]) and in multiple sequence alignment software (Promals [ 39]).
Despite the rapid advances in sequence capabilities and in bioinformatics resources for generating high quality assemblies [ 7– 9], de novo transcriptome studies in poorly characterized taxonomic groups continue to be challenging because of difficulties with annotation.
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The scientists owe their insights mainly to new technological advances in sequencing of prehistoric DNA.
Extraordinary advances in sequencing technology in the past decade have revolutionized biology and medicine.
Recent advances in sequencing technology have identified novel signaling molecules that regulate embryogenesis.
Advances in sequencing technology have significantly advanced the landscape of developmental biology research.
Recent advances in sequencing technology allow genome-scale approaches to cancer mutation discovery.
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