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A proxy for stage was based on the Binet and Rai et al. [ 12, 13] staging systems with patients classified as "advanced stage" if anemia and/or thrombocytopenia were present in the claims data [ 14].
On the other hand, advanced stage (International staging system stage III), anemia (<8.5 g/dl) and high β2-microglobulin level (⩾5.5 mg/l) were extracted as statistically significant unfavorable prognostic factors in t(14 16 -negative 14 16 -negativeementary Figure 1).
With respect to immunological stage, anemia was present in 85% of those with advanced or severe immunosuppression while only 56% of children with mild or no immunosuppression were anemic (p < 0.01).
It's at an advanced stage".
"The talks are at an advanced stage".
He did indeed have CTE at an advanced stage.
But she found the advanced stage of CTE alarming.
The negotiations, he added, are at "an advanced stage".
Unfortunately, many diseases are still only diagnosed at advanced stage.
She suffered from an advanced stage of Parkinson's disease.
Everything is at a very advanced stage.
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