The phrase "advanced severe" is not a standard or commonly used expression in written English.
It may be used in specific contexts, such as medical or technical descriptions, to indicate a high level of severity or complexity.
Example: "The patient was diagnosed with an advanced severe form of the disease, requiring immediate intervention."
Alternatives: "highly severe" or "extremely advanced".
In HIV-positive patients, CD4+ lymphocyte count or percentage-based immunological staging (not significant, mild, advanced, severe) was performed according to the WHO classification [ 30].
This research investigated the impact of familiarity on the use of five faucet designs during 1309 handwashing trials by 27 older adults, who ranged from cognitively intact to the advanced (severe) stages of dementia.
Conclusions: oral Iloprost administered for a year showed no clear benefit in patients with advanced severe leg ischaemia (PAOD III and IV).
The passage from a predominance of CD4+ cells to that of B lymphocytes in glandular infiltrates is therefore characteristic of a more advanced severe disease pattern, which is correlated with systemic manifestations and higher risk of developing lymphoproliferative disorders [ 32].
16 Patients eligible for inclusion in the study are without known history of severe hypoglycaemia, advanced atherosclerosis, severe comorbidity or advanced age which allows for tighter glycaemic control in U-TURN.
This evidence may be particularly compelling when additional PHN risk factors are present [ 2, 19], including advanced age, severe prodromal pain, severe rash, AHZ localized in the trigeminal dermatomes and brachial plexus, and symptoms of allodynia.
Diagnosis of PHN requires consideration of recognized PHN signs and known risk factors, including advanced age, severe prodromal pain, severe rash, and AHZ location on the trigeminal dermatomes or brachial plexus.
Subjects with psychiatric illness, advanced dementia, severe cognitive and functional impairment, severe motor disability after stroke, and those with severe sensory deficits were excluded.
Children were not included in the study if (i) their clinical status was severely impaired (including advanced or severe HIV-associated symptoms) or (ii) they were breastfed six months before the enrolment period to avoid recent HIV infection through breastfeeding.
Indications for surgery were advanced osteoarthritis, severe pain, and limited function/walking ability.
Of the 111 children with clinical stages 3 and 4, 56 (50%) had corresponding advanced to severe immunosuppression.
