Sentence examples for advanced operable from inspiring English sources

We conducted a prospective trial of BRAF and mitogen-activated protein kinase kinase (MEK) targeted therapy in advanced, operable BRAF mutation-positive melanoma to determine feasibility, tumor response rates, and biomarkers of response and resistance.

Aromatase inhibitors in combination with GnRH analogues have not been systematically studied as preoperative therapy in premenopausal women with locally advanced operable breast cancer.

Aromatase inhibitors in combination with GnRH analogue have not been systematically studied as primary therapy in premenopausal women with hormone receptor positive locally advanced operable breast cancer.

Following the completion of chemotherapy, pre- or postmenopausal patients with locally advanced (operable and inoperable) hormone-responsive tumours should receive endocrine therapy according to their menopausal status.

In conclusion, anastrozole (1 or 10 mg daily) effectively suppresses aromatase activity, and thereby oestrogen levels, within the breast of postmenopausal women with large or locally advanced, operable, ER-rich breast cancers.

Anastrozole (1 and 10 mg daily) effectively suppresses aromatase activity, and subsequently oestrogen levels, within the breast tissue of postmenopausal women with large or locally advanced, operable, oestrogen receptor-rich breast cancers.

Recently, rationally designed optical probes have paved a highway for the sensitive and selective detection of the toxic chemical and their design was advanced enough to operable in the aqueous environment.

However, 15% and 35% of cases in the primary operable and advanced series respectively displayed strong positive staining.

In addition, debulking of operable tumors by advanced techniques (i.e., gamma knife) is also a valuable adjunct.

Emerging new therapeutic approaches using a monoclonal antibody directed against HER-2 have yielded improved short-term survival for advanced stage [ 106] as well as operable BC patients [ 107].

"The five-story office buildings will be ecologically advanced," he said, "in the use of ceiling tiles recycled from newspaper pulp, concrete pavers recycled from torn up highways, operable windows, outlets for hybrid and electric cars, and building materials that will be manufactured within a 500-mile radius to minimize road traffic".