advanced into clinical development

USAGE SUMMARY

The phrase "advanced into clinical development" is correct and usable in written English.
It can be used when discussing the progression of a drug, treatment, or medical technology from earlier stages of research to the phase where it is being tested in humans. Example: "The new vaccine has successfully advanced into clinical development after promising results in preclinical trials."

✓ Grammatically correct

Science

Human-verified examples from authoritative sources

Exact Expressions

4 human-written examples

In this manuscript we report the design of dual Akt/p70S6K inhibitors and the evaluation of the lead compound 11b in vivo, which was eventually advanced into clinical development.

Bioorganic & Medicinal Chemistry Letters

Ponatinib (AP24534) was previously identified as a pan-BCR ABL inhibitor that pan-BCR ABLhinhibitor thatI gatekeepotentlynt, and has advanced inhibitsnical developmentheor T315Ireatment of refractory or resistant CML.

Bioorganic & Medicinal Chemistry Letters

Since the approval of Imatinib (Gleevec) in 2001, the first marketed kinase inhibitor, many additional kinase inhibitors have been advanced into clinical development.

Plosone

BMS-911543 (see Supplementary Figure S1 for structure), a highly selective Janus Kinase 2 inhibitor, exhibited favorable efficacy and safety as well as ADME properties in vitro and in animals (Supplementary Table S1) and was thus advanced into clinical development for treatment of myeloproliferative neoplasms.

CPT: Pharmacometrics and Systems Pharmacology

Human-verified similar examples from authoritative sources

Similar Expressions

56 human-written examples

Implicit is the advantageous potential of any such molecule to rapidly advance into clinical development by leveraging a proven track record in humans and a deep history of study.

ACS Chemical Biology

These alternative strategies show promise in preclinical studies, with some advances into clinical development [ 2].

BioMed Research International

While vaccines against nicotine and cocaine have advanced into clinical trials, Meth vaccine development is more difficult.

Human Vaccines and Immunotherapeutics

Several FTase inhibitors have advanced into clinical testing.

Bioorganic & Medicinal Chemistry

Some GRT drug conjugates have been advanced into clinical trials.

Advanced Drug Delivery Reviews

5c- S) (SD-8381) was advanced into clinical studies due to its superior in vivo potency.

Bioorganic & Medicinal Chemistry Letters

Compounds that have advanced into clinical trials have demonstrated mixed results.

EMBO Molecular Medicine

Expert writing Tips

Best practice

When discussing drug development, use "advanced into clinical development" to indicate that the research has progressed beyond preclinical studies and is now being tested in humans. Provide context about the specific phase (Phase 1, Phase 2, etc.) when available for more clarity.

Common error

Avoid using the past perfect tense (e.g., "had advanced") unless you are specifically referring to an action completed before another point in the past. "Advanced into clinical development" is generally used to describe a current state resulting from a past action.

Linguistic Context

The phrase "advanced into clinical development" functions as a descriptor, indicating the stage a drug, therapy, or medical device has reached. It emphasizes a transition from preclinical studies to human trials, as confirmed by Ludwig's examples.

Expression frequency: Uncommon

Frequent in

Science

100%

Less common in

News & Media

0%

Formal & Business

0%

Academia

0%

Ludwig's WRAP-UP

In summary, the phrase "advanced into clinical development" accurately describes the progression of medical research from preclinical stages to human trials. Ludwig AI confirms its grammatical correctness and suitability for scientific contexts. While alternatives like "progressed to clinical trials" exist, the original phrase effectively communicates this transition. Remember to contextualize its use with specifics about the trial phase for maximum clarity. The primary context for this phrase is in scientific literature.

More alternative expressions

Phrases that express similar concepts, ordered by semantic similarity:

entered clinical development

Uses "entered" instead of "advanced", suggesting the beginning of the clinical stage.

moved into clinical testing

Replaces "development" with "testing", emphasizing the evaluation aspect.

transitioned to clinical studies

Highlights the shift from preclinical work to studies involving human subjects.

progressed to clinical trials

Focuses specifically on the "clinical trials" phase, implying a test of medical intervention.

reached clinical stage

Indicates reaching a specific point, the clinical stage, in the drug pipeline.

undergoing clinical evaluation

Emphasizes that it is currently being evaluated in the clinical setting.

proceeded to human trials

Highlights that the research is now being tested in humans.

developed for clinical use

Focuses on the ultimate intention of the development process: its usability in medical practice.

assessed in clinical studies

Implies an active assessment, rather than simply a progression through development.

approved for clinical trials

Focuses on the approval process required before beginning clinical trials.

FAQs

What does it mean when a treatment has "advanced into clinical development"?

It means the treatment has moved beyond initial research and is now being tested in humans to assess its safety and effectiveness.

What are some alternatives to saying "advanced into clinical development"?

You can use phrases like "progressed to clinical trials", "entered clinical development", or "moved into clinical testing" depending on the context.

Is it correct to say "advance to clinical development"?

While understandable, "advance to clinical development" isn't as common. "Advanced into clinical development" is more idiomatic and suggests a completed transition.

What is the difference between "preclinical development" and "advanced into clinical development"?

"Preclinical development" refers to research and testing done in laboratories and on animals before human trials. "Advanced into clinical development" indicates that the treatment is now ready for testing in human subjects.