The phrase "advanced extent" is not commonly used in written English and may sound awkward or unclear.
It could be used in contexts discussing the degree or level of advancement in a particular field or subject, but it may require additional clarification.
Example: "The research demonstrated an advanced extent of knowledge in artificial intelligence applications."
Alternatives: "high level" or "significant degree".
The additional data analysis (this analysis has combined MTB L4-NU and MTB L3 in one group: from now onwards this shall be referred to as MTBC non-Uganda) showed that children infected with MTBC non-Uganda lineage were more likely to have cough (P = 0.048) and advanced extent (Advance/far advanced) of lung involvement (P = 0.041) compared to those infected with MTBC Uganda family.
Since advanced lung disease is positively correlated with severity of disease and hence a measure of transmissibility [ 10– 125 26] 26], we looked for differences in transmissibility among MTBC lineages, using advanced extent of lung involvement (mild or advanced lung disease) as the outcome in the logistic model.
Patients over age 55 presented with more advanced extent of disease, but the proportion did not further increase above age 65.
Limited tissue reserves of glucose [ 11] may cause an advanced extent of anaerobic metabolism in cerebrospinal fluid.
The data showed that the odds of causing advanced extent of lung disease by different MTBC lineages identified in this study area did not differ significantly (OR = 0.304, CI: 95 %; 0.039-2.326, P = 0.251) between MTBC lineages (Table 2).
Consistent with previous reports that PTHrP can promote the occurrence or development of malignant tumors through various mechanisms, our results suggested the advanced extent of breast cancer was correlated with TGF-β and PTHrP co-expression.
The secretion of IFN-γ was significantly lower in patients with far advanced radiological extent of pulmonary TB, than subjects with minimal or moderate, upon stimulation with PHA or M. tuberculosis strain.
Evidence was presented that nuclear genes were horizontally transferred between panicoid species and were subsequently adapted into the existing pathways with the effect of advancing the extent of C4 photosynthesis in some lineages [ 21].
In this era, technology has advanced to the extent that normal citizens can take regular outings to space and parapsychology ("psi phenomena": telepathy, precognition, reincarnation and the like) are common traits of the people.
Remote response technology has advanced to the extent that a robot system, if properly designed and deployed, may greatly help respond to beyond-design-basis accidents at nuclear power plants.
Fifteen years after the adoption of UN Security Council Resolution 1325 which establishes the Women, Peace and Security agenda, there is now a need to assess the impacts of gender equality efforts, and to understand why and how gender equality reforms have advanced to the extent that they have.
