The phrase "advanced compounds" is correct and usable in written English.
It can be used in contexts related to chemistry, materials science, or any field discussing complex mixtures or substances.
Example: "The research focused on the development of advanced compounds that could improve energy efficiency in batteries."
Alternatives: "sophisticated compounds" or "complex compounds".
It offers several collaboration opportunities including the development of translational research models for understanding the pathology of skin diseases, the identification of novel targets for dermatological disorders, and the identification of new uses in dermatology for existing advanced compounds.
Advanced compounds were the culmination of iterative library design and possess excellent biochemical and cellular potency, as well as acceptable PK and efficacy in animal models.
SAR of each potential hydrogen-bonding interaction site of this novel scaffold is discussed along with some preliminary genotypic profile and PK data of several advanced compounds.
A sequence of in vitro assays followed by in vivo testing in validated animal models to assess the activity against Mycobacterium tuberculosis, pharmacology and toxicity is generally used for advancing compounds against tuberculosis in a preclinical stage.
An often cited criticism in advancing compounds to in vivo studies based on in vitro bactericidal effect is the lack of its predictive value.
These results provide the basis for a novel strategy of antimalarial drug development by advancing compounds that have dual mechanisms of action.
The author cited a need to develop pre-clinical models that are more predictive of human OA progression, or accept the risks associated with advancing compounds in development that demonstrate moderate results in already established models of OA.
While continuing to advance compounds into the expensive/expansive phase 3 arena undoubtedly represents risk principally to the drug developer, this should not be confused with a lack of concern or scientific interest from regulators.
As high-dimensional omics research has advanced, the compound covariate (or compound score) has generally been held as a simpler and more straightforward approach.
Alexander Hoepping and René Smits are employees of ABX advanced biochemical compounds, Radeberg, Germany.
DOTA0,TYR3-octreotate was obtained from ABX advanced biochemical compounds (Dresden, Germany).
