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Docking studies demonstrated that benzoxepin 6b adopt an orientation similar to that of isoCA-4 at the colchicine binding site on β-tubulin.
In redefining its positive constitutional order, will Libya continue to take the path of vengeance along the lines of Iran, or can it adopt an orientation toward tolerance, and republican-style secularism, more akin to Turkey?
In this stage, all chromosomes migrate to one area of the nucleus and adopt an orientation in which all telomeres attach to the nuclear membrane (Scherthan et al. 1996).
The orientation of the PolDom monomers is in dramatic contrast to that observed in the imperfect PolDom-DNA synaptic complex (PDB: 2R9L), in which the PolDom monomers adopt an orientation where the duplex regions are on opposite sides of the complex.
Similar(56)
Molecule 48 adopts an orientation similar to that inside the B-Raf active site.
On an optimized hydrophobic surface, the AChE adopts an orientation with both good activity and stability, which has been proven by electrochemical methods.
Here, we provide biochemical evidence that carbamates covalently modify the active site of FAAH by adopting an orientation opposite of that originally predicted from modeling.
Modified Halpin Tsai equation was proposed to evaluate the Young's modulus and tensile strength of the MWNTs/phenolic composites by adopting an orientation factor and an exponential shape factor in the equation.
A model for pulsed-field electrophoresis was developed by picturing large DNA as a deformable "bag" that (i) moves with limiting mobility in a continuous electric field, (ii) adopts an orientation aligned with the field direction, and (iii) reorients after a change in field direction in a size-dependent manner.
These membrane binding sites enable reductase to sit on the endoplasmic reticulum membrane, thus reductase adopts an orientation in which the FMN, FAD, and NADP binding sites are facing towards the cytoplasmic side.
H12 in the genestein/human ERβ complex surprisingly also adopts an orientation that again exhibits fundamental differences in the length, positioning and interactions compared with the 'antagonist' orientation.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com