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If the date of diagnosis was missing in the DCR, the admission date from the NPR was used.
For inpatient isolates, the number of days from admission to culture procurement was determined by subtracting the admission date from the procurement date.
Based on the admission date from the register, we could identify the medical records anonymously from the archive and include or exclude due to the final diagnosis.
The length of hospitalisation was calculated by subtracting the admission date from the discharge date for days within the study period.
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Records were matched when admission dates from the two data sources were within two days of each other and if an International Classification of Diseases (ICD) code of I61, I63, I64, or G45 was in the primary or secondary diagnosis field on SMR01.
Person-years at risk were calculated from the admission date for the hospital visit during which BPH was first recorded to the date of first cancer (any, including bladder cancer), emigration, death or end of the observation period (December 31 , 1989, whichever occurred first after BPH diagnosis.
The time of MI symptoms onset was determined primarily using information from the medical clinic about the time of symptom onset or admission, or alternatively the admission date was obtained from the National Hospital Discharge Registry.
For each participating resident, data collected included gender, age on admission, date of admission, from where the resident was admitted, presence of an indwelling urinary catheter, systemic antimicrobial treatment, and hospitalisation in the previous 12 months, and previous ESBL, CPE, VRE, and MRSA result recorded before study commencement.
Admission serum biochemistry and blood gas results (defined as the first available results within 24 h of the recorded admission date) were extracted from the database alongside the serum biochemistry and blood gas results at 6 am (+/- 2 hours) for the 3 days following admission.
LOS was calculated by the number of days from admission date to discharge or death date.
Outcomes occurring during index admission for surgery, that is, from admission date until discharge date, were excluded for the concerned analysis.
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