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To estimate the drug acquisition costs (induction and maintenance) for both models during the progression-free period, the number of administrations, as reported in the PRONOUNCE trial, was combined with average dosing and unit costs for each drug within each regimen.
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The corrected chronological age refers to the age at the start of administration (as reported in two pivotal trials) adjusted to reflect the gestational age at the birth; for example, an infant who is 20 weeks old at the start of administration but was born at 30 wGA would have a corrected age of 10 weeks, assuming a typical 40-week gestation.
This initial temporary hyperglycemia may be due to pre-glucose loading, whilst, the extracts did not start to give their effect directly after administration, as reported before in literature [ 26].
The earlier inhibition by disulfiram of alcohol consumption in our study may be due to the more rapid absorption of the drug solution after intraperitoneal, when compared with that of the drug suspension after oral, administration as reported by the above authors.
12 Conversely, regional DC vaccination (i.e. the intra/para-tumoral injection of DC) has shown better regression of local residual or recurrent tumors compared with systemic DC administration, as is reported in animal experiments and also clinical trials.
Intestinal adult parasites were obtained from immunosuppressed hamsters 30 days after oral administration of cysticerci as reported previously [14].
Indeed, sequential measurements of protein C levels were used to guide administration of rAPC, as reported in the phase II RESPOND trial (Research Evaluating Serial Protein C levels in severe sepsis patients on Drotrecogin alfa [activated]) [ 44, 45].
However, cartilage is not innervated and thus pain reduction after GlcN administration, as has been reported in the previously mentioned NIH trial, can therefore not be explained by the effect of GlcN on cartilage tissue.
To obtain the total cost of prophylaxis, the per-protocol palivizumab costs (five administrations for all children) were adjusted for the actual number of administrations (4.1 injections on average), as reported in Pedraz et al. [45] for Spain.
It emerged this week that Murkowski had help in drafting her bill from EPA administrators from the Bush administration, as first reported by the Washington Post.
The United States Embassy in Paris denied Wednesday that the United States carried out a cyberattack to read files on computers in the Élysée Palace during the administration of President Nicolas Sarkozy, as reported in Wednesday's edition of L'Express, a French weekly.
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