Adjuvant chemotherapy for colorectal hepatic metastases: role of route of administration and timing.
In multivariable analysis (Table 5), both SOFA score on the day of cyclophosphamide administration and timing between admission and administration of cyclophosphamide were significantly associated with outcome (OR for a 1-day increase in delay 1.16 [95 % CI 1.05 1.29], p = 0.005; and OR for a 1-point increase in SOFA 1.35 [1.14–1.60]; p < 0.001).
The charts of all patients (RA and non-RA) were reviewed for: confirmation of MI and type of MI, conventional cardiovascular risk factors and other comorbidities (including prior MI), medications taken at time of MI admission, administration and timing of reperfusion therapy (thrombolysis or PCI), and post-MI events such as in-hospital death and coronary artery bypass graft surgery.
The remainder of this section of the paper will be dedicated to more practical aspects of PRM administration in dialysis centers, including mode of administration and timing of PRMs.
Drug administration and timing was strictly controlled.
Comparisons with and among these studies are hampered by heterogeneities in trial design, study populations, GLP-2 dosages, routes of GLP-2 administration, and timing of treatments.
The administration and timing of acute reperfusion therapy and in-hospital treatment with secondary prevention medications were compared between the two groups.
The dose, route of administration, and timing of P-gp inhibition were based on those described in earlier studies [ 17, 49– 51].
However, the duration of the effects of a single intracordal injection of basic fibroblast growth factor has not been established, and administration intervals and timing have yet to be standardized.
With our administration dose and timing (total dose 10 mg, 5 mg/day at days −2 and −1), we achieved the maximum peak level at day of stem cell infusion, which is lymphotoxic but still 1 2 log lower as compared with the 100 mg and the 50 mg schedules.
