According to senior administration officials, the timeframe was the result of Obama's personal request for a resolution – and reflected his impatience with political frivolity of any kind.
During the entire study period all included patients were sedated with midazolam/fentanyl and equipped with an invasive cardiac output device (PiCCO®, Maquet, Munich, Germany), enabling the tracing of changes in stroke volume (SV) within the short timeframe of fluid administration and/or the PLR test.
Post-marketing studies can detect adverse effects that occur rarely or because of extended intake, because administration occurs in a larger timeframe and study population than in the phase I-III clinical trials.
The approach is far less labor-intensive and allows rigorous quantification; for medical applications, including selections in patients, it also represents an advance for quantitative distribution analysis and ligand identification of hundreds of thousands of targeted particles from patient-derived biopsy or autopsy in a longer timeframe post library administration.
Therefore, we chose a four-week timeframe for its administration.
There are a variety of avenues the court could decide to follow that would lead to different outcomes and timeframes for the administration.
The timeframe of re-administration was the same.
In the sample of Schuler et al. [ 7], the time period between the two administrations was three weeks, a timeframe comparable to those used in our study.
Pickles told the House of Commons on Monday that a PricewaterhouseCoopers study into the administration would continue beyond the agreed timeframe and he has ordered the council to pay the costs.
Gibbs comments during Monday's press briefing were, nevertheless, the most definitive timeframe offered by the administration yet in regard to filling the opening on the court.
This probably avoided memory effects in participants' ability to report their level of PA, while at the same time administration of the questionnaire in this timeframe may have ensured stability of activity levels.
