Exact(11)
However, animal studies also showed clear toxicity with certain administration regimes.
In animal models, systemic administration regimes resembling chronic exposure to this drug (50 mg/kg, twice a day during one week), induce memory impairment.
Drug delivery schedules are key factors in the efficacy of cancer therapies, and mathematical modeling of population dynamics and treatment responses can be applied to identify better drug administration regimes as well as provide mechanistic insights (Pillis and Radunskaya 2001).
Engineered bacteria can be tailored to deliver drugs, therapeutic proteins, and gene therapy vectors with great efficiency, and with a higher degree of site-specificity than conventional administration regimes.
Of course, in reality there will be examples of growth factors and drug administration regimes where temporal variation in the concentrations at the boundary is important.
We observed no difference between single and multiple cell administration regimes, except for GFR, where multiple administrations showed no effect (supplementary material Fig. S4C).
Similar(49)
The special administration regime was introduced in the wake of the Lehman Brothers collapse to ensure the failure of an investment firm results in the minimum of disruption to financial markets.
The objective of the proposed control scheme is to provide an adequate drug administration regime for propofol to avoid overdosing and underdosing of patients.
A number of major cities have passed IRV, but its progress in more states and cities has been hindered by our inefficient election administration regime where equipment vendors think about profit first and the public interest second.
Only 58.9% of the students knew the pre-exposure administration regime for rabies vaccine.
The loss of dopaminergic neurons depends on the administration regime (from acute to chronic), ranging from 60%to90%0% [ 88].
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