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Intraperitoneal administration of single dose of cisplatin (7.5 mg/kg) was used to induce nephrotoxicity.
This disease was induced by combine administration of single ICV (intracerebroventricle) infusion of β-amyloid (Aβ) once and chronic oral administration of l-Methionine for 21 days.
The results of this comparison of Test and Reference capsule formulations of fingolimod, following administration of single 0.5 mg doses under fed conditions, show that the two compounds may be regarded as bioequivalent based on 90% geometric CIs within 80% to 125% for both AUC and Cmax.
Its first perceptible analgesic effect occurred within 7 to 13 minutes, with clinically meaningful analgesia demonstrated within 23 to 39 minutes and a peak effect within 2 hours following administration of single doses of 40 mg by IV or IM injection [2].
The combined delivery of FGF-2 and VEGF through starPEG-heparin hydrogels resulted in pro-angiogenic effects in vitro (study of cell survival/proliferation, morphology and migration) and in vivo (quantification of CAM vascularization) being clearly superior over those of the administration of single factors.
The complex changes from triggering TLR may be more beneficial than administration of single cytokines.
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These assays are powerful tools when attempting to determine the clinical implications of these low level resistant virions after the administration of single-dose nevirapine.
This study was designed to evaluate the effect of luteal-phase administration of single-dose gonadotrophin-releasing hormone (GnRH) agonist on pregnancy, implantation and live birth rates in patients who received GnRH antagonist for pituitary suppression.
While preferential drug specificity towards a target is effective against diseases that are monogenic, the administration of single-drugs has been less successful against the widely prevalent diseases affecting large population groups like cancer, cardiovascular diseases, metabolic syndromes and neurological disorders.
However, in this outbreak the infections resulted from administration of single-dose lyophilized or two-dose liquid vaccines.
Manegold et al (2001) reported on a sequential administration of single-agent GEM and DOC.
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