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The following section contains descriptions of the seven sites, the PhenX measures employed and the administration of protocols for each site.
Administration of protocols adhered to U.S. Department of Health and Human Services human experimentation guidelines.
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Hemogram was checked before each administration of protocol treatment, and serum biochemistry, electrolytes and prothrombin time were checked before each cycle.
Also excluded were patients with a history of renal, hepatic or heart failure, history of malignancy except basal cell carcinoma of the skin or cervical carcinoma in situ, or history of psychiatric disorder that might interfere with the administration of protocol drugs or follow-up.
Laypersons are a 'specialized' subset of the community who actively participate in the administration of research protocols through their work on ethics committees.
To simplify the administration of this protocol, we chose one feeding formula to be used initially.
The importance of treating cancer-associated symptoms has recently been highlighted to oncologists with evidence that that the administration of routine chemotherapy protocols are associated with a significant 30-day mortality (NCEPOD, Systemic Anti-Cancer Therapy: For better, for worse?; http://www.ncepod.org.uk/2008sact.htm).htm
An ABA design was implemented in which the participant was observed during four phases: (a) baseline, prior to the administration of the brushing protocol; (b) week 3 of implementation of the brushing protocol; (c) week 5 of implementation; and (d) 6 months after the discontinuation of the brushing protocol.
Enhanced pause (Penh), an estimator of airflow limitation measured by barometric whole-body plethysmography, was repeatedly assessed within 120 min following the administration of each treatment protocol.
These training cards will be used to ensure the proper administration of the training protocol for a particular company.
Even if the preparation of the subject and the acquisition procedure were not actually timed, an average total time for the bilateral administration of the whole protocol can be estimated.
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