Adverse effects related to radioiodine administration, graded according to the National Cancer Institute Common Toxicity Criteria version 2.0, were recorded by the study participants on structured forms approximately four days before 131I administration, and four to seven days, two to three weeks, and three months following treatment.
For patients receiving docetaxel administration, if grade 4 neutropenia, febrile neutropenia, skin/nail changes, or grade 2 peripheral neuropathy developed, dose was reduced to 45 mg m−2.
A bipartisan group of former officials recently gave the Obama administration a grade "F" for its complete lack of follow-through on any of the promises to improve accountability around the CIA and military drone strikes.
One patient stopped docetaxel administration for grade 3 hypersensitivity reaction during the first cycle.
For patients receiving sunitinib administration, if grade 3 toxicity developed, sunitinib was withheld until the toxicity was resolved to <grade 2, then treatment was reduced to 25 mg.
In the case of patients with joint symptoms prior to the start of AI administration, the grade of the symptoms at the time of exacerbation was assessed, and the pretreatment symptoms were not taken into consideration.
Local injection site reactions related to study drug were reported if occurring within 7 days of study drug administration; related grade 3 reactions consisted of hardness, pain, redness, and swelling.
"Right Answer, Wrong Score: Test Flaws Take Toll," your May 20 front-page article about the flaws in the design, administration and grading of scholastic achievement exams, addresses only part of the problem of using such exams to measure understanding.
He compared the litigation against his clients to the Bloomberg administration's grading of restaurants for compliance with health rules, which has led to some grumbling that the administration is overzealous.
It is time for this administration, which graded schools and teachers based on inaccurate and misleading numbers, to cease blaming teachers and principals and join with them in struggling to meet our students' needs.
That view, as usual, is best articulated by Washington's Dean, the pundit David Broder, who in February gave the new administration high grades for having "a cabinet of C.E.O.'s, made up mainly of men and women who have run large enterprises".
