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An interesting growing field related to liquid dosage forms is the development of administration devices.
r-hGH is administered by daily subcutaneous injection and may be given using a number of different administration devices.
Another example of administration devices is the dose sipping technology in which a pre-dosed granulated medicine is filled into a ready-to-use straw [26].
Age-appropriate administration devices (e.g., the solid dosage pen, multiparticulate counters and medicated straws) may improve the acceptability of pharmaceutical products.
Areas covered: The current approaches and novel developments in the field of age-appropriate drug delivery for pediatric patients are critically discussed including patient-centric formulations, administration devices and packaging systems.
Parents, physicians and nurses were asked to rate 19 device attributes by completing a questionnaire, and to rank four different r-hGH administration devices (including a conceptual electronic device) in order of preference.
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Specific aspects of tDCS administration, device operation and group allocation were designed to optimise the integrity of blinding.
The technology comprises small, hollow mini projectiles into which drug formulations can be loaded and administered using compressed air from an administration device which is held a few millimeters (3 10 mm) from the surface of the animals' skin.
Ultimately, the consistency with which patients use an administration device will affect the clinical results achieved.
Despite these advances in r-hGH administration device design, there is still scope for improvement.
Group discussions involving three to six individuals were conducted to assess opinions relating to r-hGH administration device attributes.
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