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MT-I/II null (MT−/−) mice and corresponding wild-type mice (MT+/+) were administrated with a single dose of DOX (15 mg/kg, i.p).
In contrast, when inactivated LASSARAB immunizations were combined with a late boost (day 28 post-prime), high levels of LASV GPC-specific antibodies were induced at later time points, especially when administrated with a TLR-4 agonist (GLA-SE).
The third group (GIII) was administrated with a daily oral dose of extract of olive leaf extract (100 mg/kg) from days 1 to 18 of gestation.
In 1995, Asahara et al. proved for the first time that such synergistic effects of bFGF and VEGF enhanced collateral growth in a rabbit hindlimb ischemia model when they were administrated with a ratio of around 1∶50 (bFGF∶VEGF) [10].
A total of 208 cycles were administrated, with a median number of five cycles given (range 1 29 cycles).
For limited-stage SCLC patients, thoracic radiotherapy was administrated with a total dose of 45 Gy and at hyperfractionated technique of 1.5 Gy/fraction twice daily.
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The corresponding control mice were administrated with an equivalent volume of vehicle.
Contrast-enhanced images in the arterial phase are obtained during bolus intravenous injection of 90 130 ml of iodinated high-concentration non-ionic contrast medium, administrated with an automated injector at a flow rate of 3 4 ml/s through an antecubital vein.
Rats in the NC, sham, and OVX control groups were administrated with an equal volume of distilled water to that in the decoction treatment groups.
Then the animals were administrated with an intravenous bolus injection of F-FDG (200 250 µCi/rat) dissolved in 0.5 mL of saline.
Also this vaccine needs to be administrated with an adjuvant in adult cattle; it does not interfere with serological diagnosis and it is safer in pregnant animals but only has been tested in some countries [ 22].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com