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Once nanoparticles were administrated into the organism, they will enter through the blood vessel wall and then participate in blood circulation.
Four hours after GTN injection, locomotor activity assessment and nociceptive tests were re-evaluated; afterwards, 20 μl of 5% formalin were administrated into the upper right lip in order to assess formalin-induced orofacial pain.
It was also reported that PLA- and PLGA-based nanoparticles can be rapidly cleared in the liver and captured by the reticuloendothelial system (RES) when they are administrated into the blood circulation [14, 15].
The in vivo model utilized the rat cerebral vasculatures as a paramagnetic agent compartment, and intravascular agents (Gd-DTPA 30 BSA Gd-DTPA 30 BSAated into the compartment via bolus injections.
Heparin was administrated into the water and was replaced every 48 h.
Strikingly, when OVA was administrated into the site of laser illumination, a synergistic effect was observed on APC motility.
Similar(46)
When subcutaneously administrated into normal rats, the PIns showed a faster rate of onset of action and a shorter duration of action compared with regular insulin, similar to the pharmacokinetic characteristics of insulin Lispro.
To verify the role of corticosterone in chronic stress on liver injury repair by MSCs, corticosterone was subcutaneously administrated into mice at the third day after MSCs injection in parallel with restraint stress in another group.
Thus, we proposed that FSH might play an important role in preserving ovarian survival during cryopreservation by vitrification and avascular transplantation; hence, in this study, 0.3 IU/mL FSH was administrated into vitrification solution and the function of FSH was explored in the ovarian vitrification and transplantation.
Therefore, with the aid of US, plasmid DNA, and BLs were systemically administrated into hind-limb ischemia area in the experiment.
Self-assembling peptide nanofibers (O-Q11), in which the OVA323-339 epitope, derived from chicken egg OVA, and Q11 were linked via a spacer, were subcutaneously administrated into mice and elicited high IgG titers in the absence of an additional adjuvant.
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