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The pre-publication history for this paper can be accessed here: http://www.biomedcentral.com/1472-6831/11/10/prepub The authors want to thank the Faculty of Medicine and Dentistry, University of Bergen for financing the study (Grant No. 101330), and professor Kristin S. Klock for administering the data collection both in 1997 and 2007.
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School nurses and headmasters administered the data collection.
These were mainly developed for the study coordinator and data managers to help administer the data entry process and to manage data updates.
It was observed that the women were able to administer the data collection tool (Additional file 1) following a brief orientation session.
In each country, data collectors were selected based on previous experience and credentials and underwent a 2-3 week training on the study instruments and the methods required to properly administer the data collection tools.
To allow direct comparison of the results from individual mice and to normalise for the levels of radioactivity administered, the data are expressed as a ratio of level of radioactivity retained by synovium over that in skin control per mm of tissue at each time point.
LB was the primary researcher, responsible for collection of data by administering the instruments, data analysis and writing the manuscript.
PB was responsible for administering the survey and data acquisition.
The information obtained from questionnaire surveys is constructed through the process of designing and administering the questionnaire and compiling the data that result.
Only nurse counsellors and the research assistant knew the results of the allocation, as they were responsible for enrolling and assigning subjects to groups and administering the intervention, but not the data analyst or project investigators.
Given the complex nature of the disease and difficulty related to administering the treatments and scoring the data, the level of repeatability observed was high for all traits, indicating that biologically meaningful QTL are responsible for much of the phenotypic variation reflected in the population.
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