However, in view of the autoimmunogenic potential of inhibiting TNF, we tested TNF inhibition as a means to interfere with the inflammatory response in SLE by administering only an induction regime of four infusions of infliximab within 10 weeks rather than by planning for long-term therapy.
Unlike in a toxic response, in which everyone exposed develops the response if a sufficient dose is administered, only a small fraction of the exposed population is sensitized by an allergen, regardless of the dose.
The introduction of balanced incomplete block (BIB) spiraling, where each student is administered only a small subset of the total item pool, was another important innovation as that made it possible to maximize the coverage of the assessment constructs while reducing the burden on the individual test taker.
Although paper-and-pencil versions of the GRE exams are administered only a few times a year--thus allowing test preparation firms to hold large, profitable classes--the computer tests have been available several days a week.
First, in the present study we administered only a single, acute injection of Met, whereas prior studies administered Met, chronically.
The healthy donors were administered only a growth factor (G-CSF) at a dose of 5 μg/kg/day.
In the mentioned studies, the NOS inhibition was administered only a few hours before the CYP treatment.
While the structured clinical interview was developed to be administered face to face by a mental health specialist, in our trial it was feasible for the generalist nurses to administer only a shortened version of the depression module by telephone.
Our results further indicate that clinicians or researchers with limited resources who administer only a single memory test should opt for a much more stringent cutoff (i.e., −2 SD below normative reference data) to determine episodic memory impairment with comparable accuracy to two measures.
CONCLUSION: For patients with localized esophageal cancer, whether or not preoperative chemotherapy is administered, only an R0 resection results in substantial long-term survival.
