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Further evidence in support of the antioxidant mechanism is seen in the reduction in malondialdehyde levels of the liver and kidney compared to that of the group administered with only carbon tetrachloride.
Treatment was safely administered with only seventeen adverse events resulting in treatment discontinuation.
TEGAFOX cycles were administered with only a reduced dose of UFT in 59 cycles (13%) and with only a reduced dose of L-OHP in 9 (2%), whereas 16 (4%) cycles were administered with both drugs at reduced doses.
Surgery is the principal modality in the curative intent treatment of patients with MPM and would be administered with only a palliative goal or, especially in those with localised disease.
Ferumoxytol can be injected rapidly IV at doses of 510 mg with no test dose, and therefore a full treatment course (1.02 g) can be administered with only two clinic visits.
Administration of MK-8776 18 h after gemcitabine caused significantly delayed tumor growth compared to either drug alone, or when the two drugs were administered with only a 30 min interval.
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This brain-to-plasma ratio was (average ± standard deviation) 0.9 ± 0.6 in control animals and 0.6 ± 0.4 in kainate-treated animals pre-administered with only vehicle.
However, Doxycycline (1/2 MIC) or CZX (1.0 μg/ml) in combination with nanobubble-enhanced ultrasound dramatically reduced the number of inclusions compared with that administered with antibiotics only.
Mice from control group were administered with vehicle only.
No tumor was developed in mouse either untreated or administered with RAN only.
SH-SY5Y cells were incubated for 24 hours with a final concentration of freshly prepared 10 μM Aβ42 and controls cells were administered with buffer only (prepared as described in Soura et al., 2012 [ 33]).
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