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In preclinical studies, brivanib has shown strong antiangiogenic and antitumour effects on tumour cells across a range of tumour types, including colon, breast, liver and lung (Bhide et al, 2006, 2010; Huynh et al, 2008), and no evidence of evasive resistance when administered to RIP-Tag2/Bl6 mice (Allen et al, 2009).
In the I.C.U., we found her entangled in a web of I.V.s, tubes, and wires, paralyzed by Rocuronium (called "the rock" by everyone there), which had been administered to prevent her from ripping out her breathing tubes.
was administered to all animals.
It seemed important not to rip it.
She likes to rip up blankets.
Detroiters are out to rip us off.
It's hard to rip and run, after all, without something to rip.
"Tear" like to RIP.
I want to rip this shackle off".
The rDNA repeat (Y1) exhibits selective susceptibility to RIP mutation.
Interestingly, in VdLs.17, RIP mutations affected members of the Gypsy but not Copia superfamilies of retrotransposons, indicating either a differential susceptibility to RIP by different types of TEs or introgression by horizontal transfer of already RIPed sequences [ 2].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com