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When PI3K inhibitor was administered specifically to the nucleus accumbens-shell, systemic quinpirole-induced behavioural activation was significantly suppressed.
No antimicrobial prophylaxis was administered specifically for the nerve catheter insertion, but nearly all patients received a single-shot perioperative antibiotic prophylaxis after catheter placement before surgery.
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In conclusion, we show that the endocannabinoid system is downregulated in chronic pancreatitis and that its augmentation via exogenously administered cannabinoids specifically reduces activation of pancreatic stellate cells.
Information on their socio-demographic characteristics was collected through a questionnaire administered by specifically trained midwives.
Imatinib mesilate (Glivec®, Novartis Pharmaceuticals) is an orally administered treatment specifically targeting cancerous cells (Druker et al, 2001a, 2001b).
Systemically administered TR specifically abrogated the formation of new blood vessels, while no evidence for damage in other tissues or in existing blood vessels was observed.
Furthermore, VA questions were neutrally formulated and administered by specifically trained Ivorian field workers in order to minimize any potentially occurring cultural bias.
Therefore, this study was initiated to investigate the hepatoprotective activity of PA when administered alone, specifically in thioacetamide-induced cytotoxicity, with in vitro experiments using WRL-68 cell line.
The recent recognition of increased intestinal permeability (leaky gut), which enables access of unfavorable gut factors to the liver, is another very promising therapeutic strategy, either by eating pro/prebiotics or by administering treatments specifically dedicated to blocking intestinal permeability.
Even when administered intraperitoneally it specifically ablates TRPV1 expressing nociceptors.
By chemically conjugating these peptides to an anti-myosin heavy chain antibody, the peptides could be administered intravenously and specifically targeted to the site of the myocardial infarction.
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