Exact(1)
Table 1 Degree of baseline acidemia and base deficit in DKA patients with bicarbonate administered Reference Population Nature of study Mean initial blood indices pH Base deficit Bicarb (mmol/L) Addis 1964 [29] A. (N = 3) Case series 6.94 Mostly unavailable Kuzemko 1969 [30] P. (N = 6) Case series 7.05 23 8.0 Zimmet 1970 [4] A. (N = 11) Case series 7.09 24 4.4 Soler 1972 [22] A+P.
Similar(59)
Second, they may be designed and administered without reference to information that is used by providers of health care.
All doses were administered at reference centers called "application hubs" which are outpatient departments.
One audiologist or one of two research assistants administered the reference audiogram and the digit recognition task.
Tajima's D [ 48] and Fu's F S [ 49] were estimated and a mismatch distribution test was administered with reference to the method of Schneider et al. [ 50].
As all subjects in the present study were women, the optimal approach would therefore be to administer the reference dose and the fruit drinks at the same point in the menstrual cycle – that is, 4 weeks apart.
Participants were administered index and reference standard tests concurrently.
This protocol determines that PEG-IFN is administered weekly at reference centers called "application hubs" which are outpatient departments.
Reference blood glucose levels were measured by the YSI 2300 STAT Plus (YSI, Yellow Springs, OH) every 30 min. Carbohydrate was administered when the reference blood glucose level dropped below 70mg/dll.
Bioequivalence studies compare the pharmacokinetic parameters of two drug forms (test vs. reference) administered sequentially to volunteers and are also based on the instrumental determination of the drug or its active metabolite(s) [ 6, 7].
For each 1 unit of change in the log of trophozoite dose administered to the reference experimental host "Gerbil," the odds of cyst shedding increased 2.67 times (P value < 0.0001; CI: 1.81, 3.94), whilst the odds ratio corresponding to an increase of one in log dose in cysts was 0.57 times that in trophozoites (P value = 0.002; CI: 0.41, 0.81).
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