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In addition, administered quantities of antimicrobials were recorded monthly for each patient care location of the medical-surgical service and defined daily doses (DDDs; World Health Organization Center for Drug Statistics Methodology) were calculated.
It remains unclear whether a neutralizer sodium thiosulphate needs to be added to such administered quantities, but we believed that the addition of sodium thiosulphate was necessary, because our study involved elderly patients and patients who have malfunctioning kidneys, and also because the combined usage of systemic chemotherapy was one of the assumptions of the study.
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Data extracted included the number of thyroid hormone prescriptions dispensed in England per year, the cost of these prescription items and data to allow the calculation of the approximate prescription length administered (quantity of tablets per prescription).
It has been shown in volunteers that renal clearance of lactulose but not of rhamnose is dependent on the intravenously administered quantity of the respective sugar [ 12]: urinary lactulose recovery was significantly lower after intravenous administration of a high dose in comparison with the regular dose.
When administered in quantities similar to those produced endogenously in response to endotoxin, cachectin causes hypotension, metabolic acidosis, hemoconcentration, and death within minutes to hours, as a result of respiratory arrest.
We have administered similar quantity and type of measures to family caregivers with no negative sequelae apparent [ 33].
This result confirms that the rats' kidneys were affected only when administered high quantity of the extract (≥8 g/kg bw).
Therefore, if we were reoperating on this patient under general anesthesia, we would administer sufficient quantities of intramuscular midazolam before inserting an intravenous catheter.
This inability to deliver therapy to an area of interest in the GI tract leaves only the curative options of administering large quantities of drugs or surgical intervention.
In this way, a broad-based immune response directed against multiple antigenic proteins associated with the pathogen can be elicited without the need to manufacture and administer large quantities of protein, much of which will be immunologically irrelevant or potentially even reactogenic.
In the arterial injections of cisplatin, 75% of the cases were administered the scheduled quantities of cisplatin, whereas 5% were administered 50% or less of the scheduled quantities of cisplatin.
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