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Muscles were subjected to an intermittent stimulation protocol in which a 333 ms stimulus train per minute was administered over a range of 1 to 120 Hz.
In studies in obese rhesus monkeys, K-111 administered over a range of doses and time periods significantly improved hyperinsulinemia and increased glucose uptake, confirming the beneficial effects on insulin sensitivity observed in rodents (Bodkin et al. 2003a, b; Schäfer et al. 2004).
A phase 1 study of bosutinib monotherapy administered over a range of escalating doses in patients with advanced solid tumours demonstrated a confirmed PR in one patient with breast cancer, an unconfirmed CR in one patient with pancreatic cancer, and SD in five patients with colorectal or lung cancer lasting 22 50 weeks (Daud et al, 2012).
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Treatment was administered over a mean infusion time of 10 min (SD 6, range 3 to 30).
A total of 151 infusions were given, ranging in dose from one to 20 mg, each administered over a one to four hour period.
cell−1, administered over a 48 h period at a concentration of 150 cells mL−1.
Intervention: A course of 15 acupuncture treatments was administered over a 7½-week period.
In the present study, auditory stimulation was administered over a 6 h period prior to sleep.
Single daily injections of BrdU were administered over a 12 d period.
The surveys were administered over a two-week period.
were administered over a period of 20 min.
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