Cryoprecipitate is indicated for use in acquired hypofibrinogenaemia and is administered in a wide range of clinical settings, the most common of which is cardiac surgery, accounting for ∼32 45% of all transfusions.
Development of the CRU scale was guided by two key principles: (1) brevity - the scale was required to be less than 10 items so that it could be easily administered as part of a larger survey in busy resource-stretched nursing homes; and, (2) generality - the scale was intended to capture the concept of CRU broadly so that it could be administered in a wide range of nursing home settings.
Training will be required to convince potential users that IRT-derived measures are indeed feasible to administer in a wide range of settings, easy to interpret, valid across countries and cultures and meaningful to users, and to accelerate the learning curve associated with the use of CAT.
In brief, measurements administered comprised a range of clinical and neurological assessments and structured questionnaires, including an informant interview, which were administered at the participants' homes by health workers or junior doctors (in Cuba and China), all of who received 1 week of training.
A phase 1 study of bosutinib monotherapy administered over a range of escalating doses in patients with advanced solid tumours demonstrated a confirmed PR in one patient with breast cancer, an unconfirmed CR in one patient with pancreatic cancer, and SD in five patients with colorectal or lung cancer lasting 22 50 weeks (Daud et al, 2012).
Muscles were subjected to an intermittent stimulation protocol in which a 333 ms stimulus train per minute was administered over a range of 1 to 120 Hz.
The data collection was supervised by nurses and data supervisors with many years of experience in administering a range of mental health-related instruments.
A self-complete questionnaire was administered in classrooms asking a range of questions on socioeconomic circumstances, health status, lifestyles and parenting.
Non-computerised methods may confer the advantage of being easy to administer across a range of different assessment circumstances in clinical settings, and might also be more appropriate for assessing individuals who experience difficulty or are uncomfortable in completing computer-based assessments.
