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Therefore metformin and linagliptin can be safely administered in a combination therapy without dose adjustments.
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None the less great progress has been made in the field of antiretroviral drugs, which have been administered in a triple combination since 1996 and have reduced the death rate in the West by 90% [ 3].
The additivity and safety of tafluprost and timolol administered in a non-fixed combination (NFC) have been demonstrated in two randomized, double-masked, parallel-group, multicenter clinical studies [ 25, 26].
BEGIN Once Long is the largest phase 3 study in the clinical development program of insulin degludec and was designed as a 52-week, treat-to-target trial to compare the efficacy and safety of insulin degludec with those of insulin glargine, both administered in a basal regimen in combination with metformin, in insulin-naive participants with type 2 diabetes inadequately controlled with OADs.
Of the 16 phase I studies included in uni- and multivariable analyses, two studies employed 'standard' chemotherapy administered in a novel schedule or in combination with biological modulators.
This was even the case when the plant combination was administered in a tenfold higher human equivalent dosage - a finding consistent with the very good tolerability of CLR in the pilot study.
Ketamine is different in part because it's most effective as an IV drug, one that must be administered in a hospital or clinic, often in combination with other strong drugs like Versed, to counteract its hallucinogenic effects.
In the present study, we administered in a 3-week-based regimen the combination of L-OHP 5FU/LV EPI L-OHP 5FU/LV EPIerasy to patients with locally advanced, recurrent or metastatic gastric cancer.
In conclusion, our data show that 5-FU, MMC and CDDP can be safely administered in combination, and that such a combination may have a therapeutic activity, similar to more aggressive regimens, or regimens including new and much more expensive drugs.
Lanreotide was mainly administered in combination with everolimus (73 combinations) or sunitinib (61 combinations).
Conclusion: A vasodilatator, when administered in combination with a vasopressor such as epinephrine during cardiopulmonary resuscitation, increases coronary perfusion pressure.
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