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When the antibiotic was administered for longer than 15 days, we observed the emergence of resistance of P. aeruginosa to all antipseudomonal antibiotics, except to amikacin.
Only 14 studies measured the effect of ICS, when administered for longer than one year, on hypothalamo-pituitary-adrenal function, despite the serious and potentially fatal consequences of this type of adverse reaction [37].
Vasoactive drugs and neuromuscular blockers were administered for longer in the HFOV group.
However in these two rat studies CPF was administered for longer periods than in the present mouse study.
This may explain the attenuation on oxygenation, when INO is administered for longer than 24 hours [ 4].
Patients with srf-NSIP were defined as having a history of steroid use at doses above 10 mg per day administered for longer than 3 months.
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Despite the fact that some of these drugs with serotonergic properties are frequently administered for a longer period of time to patients in the ICU and MCU, most physicians currently do not consider serotonergic toxicity as a possible cause of delirium.
The higher doses (1.5 and 2.0 mg/kg body weight/d) of the nano-gold administered for the longer time period had a pro-inflammatory effect, as indicated by an increase in the level of interleukin 6 and ceruloplasmin activity as well as the erythrocyte sedimentation rate.
In the main, the pharmaceutical interventions were administered for a longer duration than the pheromone interventions.
Although cefixime is recommended as a drug of choice by the World Health Organization (WHO) for the treatment of resistant typhoid fever [10] it is relatively expensive in South Asia and has to be administered for a longer duration than the currently used fluoroquinolones.
This difference may be because, in the latter study, preoperative chemotherapy was administered for much longer (16 – 24 weeks).
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CEO of Professional Science Editing for Scientists @ prosciediting.com