The phrase "administered during development" is correct and usable in written English.
It can be used in contexts related to medical, educational, or software development processes where something is given or applied throughout a developmental phase.
Example: "The medication was administered during development to monitor its effects on the subjects."
Alternatives: "given throughout development" or "provided during the development phase".
In females, gonadal steroids administered during development can partially masculinize the telencephalic areas, and in adulthood can increase the size of syrinx muscles.
Studies in experimental animals have shown that very low doses of endocrine-disrupting chemicals (Melnick et al. 2002), in particular BPA, in the range of human exposures can exert effects if administered during development (Markey et al. 2005).
We reported that IIS reduction protected animals from Aβ1 42 mediated paralysis in a DAF-16 and HSF-1 dependent manner when administered during development and adulthood [ daf-2, daf-16 and hsf-1 RNAi treatments affects neither Aβ expression levels nor the Aβ total protein amounts (Cohen et al., 2006)].
Low-level exposure to estrogenic compounds administered during fetal development results in a region-specific proliferative growth response (Timms et al. 2005; vom Saal et al. 1997).
When administered during embryonic development, RA also acts as a potent teratogen in all vertebrates and even in certain invertebrates [1] [3].
In strong support, multiple cycles of intravenous infection and subsequent elimination with primaquine (PQ), a parasiticidal drug cure, administered during liverstage development (allowing limited antigen presentation by infected hepatocyte [268] before PQ-cure) builds robust protection to natural challenge [129].
If gene therapy is administered during the development phase of the humoral response (early treatment), FIX-specific Tregs can interfere with B-cell maturation.
Methylazoxymethanol (MAM) and nitrogen mustard (HN2) are two established genotoxicants that reproducibly disrupt neuronal development when administered during the fetal or neonatal period of CNS development (Cattabeni and Di Luca 1997; Ferguson 1996; Graef et al. 1948; McDonald and Asano 1961).
The postnatal exposure to these pesticides enhanced the effect of the same pesticides administered during adulthood, relative to exposures during development only or adulthood only.
However, there is also some evidence that these drugs may be potentially harmful to embryonic or fetal development when administered during pregnancy.
This is especially true when therapeutics are administered during early stages of active tissue development.
