Exact(2)
Locally administered, concentrated heat, which was recognized by the patients as a very short and targeted induction of almost painful high temperature on the skin, led to a fast improvement of symptoms.
To test the hypothesis that there is a cause-and-effect relationship between maternal exposure of polyphenol-rich substances in late pregnancy and fetal ductal constriction, we administered concentrated amounts of mate tea, green tea, and grape juice to 13 near-term (more than 120 days of pregnancy) ewes as the only source of liquid.
Similar(58)
Thrombocytopenic patients were administered platelet concentrates before the biopsy until the platelet count reached at least 60,000/ml.
The administered fibrinogen concentrate [5.7 (0.7) g, representing ∼285 ml] restored fibrinogen plasma to baseline levels without affecting PT and platelet count.
The mean dose of 6.5 g fibrinogen concentrate administered here was higher than the doses administered in acquired hypofibrinogenaemia in other studies, including cardiac surgery patients.
In conclusion, this retrospective analysis showed that fibrinogen concentrate administered for haemostatic therapy in cardiovascular surgery was effective in increasing the plasma fibrinogen level and contributed to the correction of bleeding.
In addition, a favourable survival rate was observed in patients administered with fibrinogen concentrate with or without prothrombin complex concentrate guided by ROTEM.
The decision whether to administer fibrinogen concentrate had to be made within 10 min after CPB when diffuse bleeding was diagnosed.
Nevertheless, caution is required when administering fibrinogen concentrate for the treatment of bleeding after ACB, because there are few data on the influence of this therapy on graft patency or on its safety in this setting.
It remains to be established whether administering fibrinogen concentrate as prophylaxis or for correction of bleeding in a dosage adjusted according to bodyweight, actual fibrinogen level or fibrin-based clot firmness is a more viable strategy when using fibrinogen concentrate as haemostatic therapy for severe bleeding post-CPB.
Twenty-eight TP patients required platelet transfusions, and 81% of the 311 RBC concentrates and 85% of the 70 plasma concentrates administered during the study were infused to TP patients.
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