Unlike separately administered components, such conjugates have the potential to deliver precise antibody-adjuvant ratios to the tumor microenvironment following intra-tumoral or systemic delivery.
A surveyor administered components of the baseline survey in the wrong order.
The PARCA score (both parent report and parent administered components) has been validated and was found to predict performance on the Mental Development Index of the Bayley Scales of Infant Development II [ 58, 59].
Nursing time associated with administering components was already included in the bed day unit costs used to cost inpatient length of stay and so was not costed separately.
Tetanus toxoid (TT) and diphtheria toxoid (DT), or the mutant form of diphtheria toxin, CRM197, are currently administered as components of multivalent formulations, such as DTP (along with a pertussis component) or DTP-Hib (with pertussis and Haemophilus influenzae conjugate).
Significantly, the therapeutic efficacy of Fn14-TRAIL could not be recapitulated simply by administering its component parts (Fn14 and TRAIL) as soluble agents, either alone or in combination.
Physiotherapists administering this component of the intervention will receive extra training in cognitive behavioural therapy (CBT).
A strict quantitative test of synergy requires measurement of the effects of each component and of the combined components administered under identical conditions.
Main Outcome Measures: We administered the disability component of the Late Life Function and Disability Instrument.
